File:Serpin mechanism.png
Size of this preview: 725 × 599 pixels. Other resolutions: 290 × 240 pixels | 581 × 480 pixels | 929 × 768 pixels | 1,239 × 1,024 pixels | 1,800 × 1,488 pixels.
kuleha na ku anama hixitalo (1,800 × 1,488 ku anama na leha hi ti phikisele, Vukulu bya fayili: 513 KB, muxaka waMIME: image/png)
Nkomiso
| Description |
English: Serine proteases operate by a two-step catalytic mechanism. First, the substrate (blue) is attacked by the catalytic triad (red) to form an acyl-enzyme intermediate. The intermediate is typically resolved by hydrolysis by water. However, when the reactive centre loop (RCL) of a serpin is attacked, the conformational change (blue arrow) pulls the catalytic triad out of position, preventing it from completing catalysis. (Based on PDB: 1K9O, 1EZX) |
| Date | |
| Source | Own work |
| Author | Thomas Shafee |
Nawu wo pfumelela
I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
Matimu ya fayili
thlava eka siku/nkarhi leswaku u vona leswi fayili ayirixiswona hi knarhi walowo
| Siku/Nkarhi | Xifanisonyana | Mpimo | Mutirhisi | Nhlamulo | |
|---|---|---|---|---|---|
| Sweswinyana | 09:56, 22 N'wendzamhala 2015 | | 1,800 × 1,488 (513 KB) | Evolution and evolvability | Higher resolution |
| 05:19, 19 N'wendzamhala 2015 |  | 1,362 × 1,126 (300 KB) | Evolution and evolvability | Minor arrow correction | |
| 05:08, 19 N'wendzamhala 2015 |  | 1,362 × 1,126 (300 KB) | Evolution and evolvability | added arrow and removed transparency | |
| 05:04, 19 N'wendzamhala 2015 |  | 1,362 × 1,114 (360 KB) | Evolution and evolvability | Cross-wiki upload from en.wikipedia.org |
Ntsengo wakutirhisiwa ka fiyili leyi
Kuhava tluka leri khwekelaka eka fayili leyi
Global file usage
The following other wikis use this file:
